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Hygromycin B solution

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Formula: C20H37N3O13
CAS: 31282-04-9
search Element: hygromycin solution

Identification

Structural Formula
Hygromycin B solution
CAS:
31282-04-9
EINECS:
250-545-5
Molecular Formula:
C20H37N3O13
MDL:
MFCD06795479
SMILES:
CN[C@H]1C[C@H]([C@@H]([C@H]([C@@H]1O)O[C@H]2[C@@H]3[C@H]([C@H]([C@H](O2)CO)O)OC4(O3)[C@@H]([C@@H]([C@H]([C@H](O4)[C@H](CO)N)O)O)O)O)N
Synonym:
hygromix-8 ; hygromix2.4 ; hyaromycin b ; hygrovetine ; hygromix ; 2-3)-o-b-d-talopyranosyl-(1® ; hygromycin b ; hygromix 2.4 ; hygrovetin ; d-streptamine,o-6-amino-6-deoxy-l-glycero-d-galacto-heptopyranosylidene-(1® ; antihelmycin ; 5)-2-deoxy-n3-methyl- ; 950u/mg ; hydromycinb ; hygromycinb (7ci)


Description

Hygromycin B is an aminoglycoside antibiotic substance naturally produced by Streptomyces hygroscopicus, which also shows anthelmintic activity. Hygromycin B has been shown to effectively inhibit translocation of mRNA and tRNAs on the ribosome in both bacteria and eukaryotes and also has a subtle effect on decoding fidelity as it slightly increases aminoacyl tRNA (A-site tRNA) affinity. Suitable for the selection of cells transfected with Escherichia coli hygromycin resistance gene (hyg or hph), as well as for the maintenance of the Hygromycin phenotype of resistant cells. Consistent with its more specific effect on translocation, hygromycin B exhibits monophasic inhibition of polypeptide synthesis, suggesting that it binds to a single site on the ribosome.


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Prices & Availability




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Properties for Hygromycin B solution

Molecular Weight:
527.60 g·mol−1
Density:
1.67 g/cm3
Melting point:
160-180 °C
Boiling point:
897.6 °C at 760 mmHg
Flash point:
496.7 °C
Solubility:
H2O: 50 mg/mL As a stock solution. Stock solutions should be stored at 2-8 °C. Stable at 37 °C for 30 days.
Physical Description:
amorphous solid or tan powder.
Transport Information:
UN 3462 6.1/PG 1
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Hazard Statements

GHS05

GHS05
Corrosive
  • Corrosive to metals, category 1
GHS06

GHS06
Toxic
  • Acute toxicity (oral, dermal, inhalation), categories 1, 2, 3
GHS08

GHS08
Health hazard
  • Respiratory sensitization, category 1
  • Germ cell mutagenicity, categories 1A, 1B, 2
  • Carcinogenicity, categories 1A, 1B, 2
  • Reproductive toxicity, categories 1A, 1B, 2
  • Specific target organ toxicity following single exposure, categories 1, 2
  • Specific target organ toxicity following repeated exposure, categories 1, 2
  • Aspiration hazard, categories 1, 2

Safety & Transport Information

Risk Codes:
R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed
R26/27/28 - Very toxic by inhalation, in contact with skin and if swallowed
R36 - Irritating to eyes
R40 - Limited evidence of a carcinogenic effect
R41 - Risk of serious damage to eyes
R42/43 - May cause sensitization by inhalation and skin contact
Safety Codes:
S22 - Do not breathe dust
S23 - Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer)
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S28 - After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer)
S36 - Wear suitable protective clothing
S36/37 - Wear suitable protective clothing and gloves
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
Hazard Symbols:
T+, Xn, T
Hazard symbol T Hazard symbol Xn Hazard symbol T+
Storage temperature :
2-8°C
RID/ADR certification :
UN 3462 6.1 / PG 1
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Alternative Distributors of [Hygromycin B solution]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Molekula GmbH | World Biopharma Group Limited / World (Jiangsu) Industry Co.,Ltd | East Chemical Industry Co., Ltd. | World Industry Co. Ltd., (Factory) | Discovery Fine Chemicals Limited | Suzhou Rovathin Pharmatech Co., Ltd | Share Chemical Co., Ltd. | Taizhou Chemedir Biopharm-Tech Co., Ltd. | Lanospharma Laboratories Co., Ltd. | Jinan Great Chemical Co., Ltd. | Carl Roth GmbH + Co KG | Jinjiangchem Corporation | Cfm Oskar Tropitzsch GmbH | Beijing Yangguang Furuide Chemical Co., Ltd. | Watson International Ltd | Jinan Haohua Industry Co., Ltd.

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