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1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine

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Formula: C41H78NO8P
CAS: 4004-05-1
search Element: phosphoethanolamine dioleoyl glycero
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Identification

Structural Formula
1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine
CAS:
4004-05-1
EINECS:
Molecular Formula:
C41H78NO8P
MDL:
MFCD00057986
SMILES:
CCCCCCCCC=C/CCCCCCCC(=O)OC[C@H](COP(O)(=O)OCCN)OC(=O)CCCCCCCC=C/CCCCCCCC
Synonym:
18:1 pe ; l-a-phosphatidylethanolamine dioleoyl ; dioleoylphosphatidylethanolamine ; 1,2-dioleoyl-sn-glycero-3-phosphorylethanolamine ; dioleoyl phosphoethanolamine ; ethanol, 2-amino-,dihydrogen phosphate (ester), monoester with 1,2-diolein, l- (8ci) ; 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine ; 9-octadecenoic acid(9z)-,1,1'-[(1r)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl]ester ; pe(18:1(9z)/18:1(9z)) ; l-beta,gamma-dioleoyl-alpha-cephalin ; 9-octadecenoicacid (9z)-, (1r)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediylester (9ci) ; 1,2-dioleoyl-sn-glycero-3-phosphatidylethanolamine ; l-?,?-dioleoyl-?-cephalin ; 9-octadecenoic acid (z)-,1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester, (r)- ; dioleoyl phosphatidyl ethanolamine ; dioleoyl-l-a-phosphatidylethanolamine ; olein, 1,2-di-, 2-aminoethyl hydrogen phosphate, l- (8ci) ; coatsome me-8181 (dope) ; coatsome mc 8181 ; 1,2-dioleoyl-sn-glycero-3-pe ; dope ; coatsome me8181


Description

1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE) is a phospholipid emulsifier that has been used for improved DNA-liposome complex transport across membranes. Commonly used with the cationic emulsifier DOTAP ( 3-trimethylammonium-propane)(sc-202589), DOPE reduces the toxic effects of DOTAP alone and has been shown to have a high DNA trapping efficiency of 89% at a DOTAP:DOPE ratio of 2:1 in emulsions. The compound is ideal for use in gene transfer studies for both conditions with serum, in vivo, and without.


Suppliers

Create Chemical Co., Ltd.
CC22506750
+
Lori Industry Co., Ltd
LI19805940
+
Santa Cruz Biotechnology, Inc.
202002
Dayang Chem (Hangzhou) Co.,Ltd.
DC279011160
+
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CAS equal suppliers

DOPE
BOC Sciences
BS48144
Dioleoyl phosphoethanolamine
Chemieliva Pharmaceutical Co., Ltd.
CP19605880
Dioleoyl phosphoethanolamine
Leap Chem Co., Ltd
LC10083024
Dioleoyl phosphoethanolamine
Finipharma Ltd
F7841568
1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine, fluorescein-labeled
Santa Cruz Biotechnology, Inc.
sc-297912
(Z)-(2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dioleate
BLD Pharmatech Ltd
BP1663249896

Prices & Availability




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Properties for 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine

Molecular Weight:
744.03 g·mol−1
Density:
1.008 g/cm3
Boiling point:
759.2 °C at 760 mmHg
Flash point:
413 °C
Solubility:
Soluble in water (partly), chloroform, methanol, 100% ethanol, 2-propanol, tetrahydrofurane, methylene chloride, and CHCl3:MeOH (9:1) (25 mg/ml).
Physical Description:
lyophilized powder
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Safety & Transport Information

Risk Codes:
R20 - Harmful by inhalation
R22 - Harmful if swallowed
R36/38 - Irritating to eyes and skin
R38 - Irritating to skin
R40 - Limited evidence of a carcinogenic effect
R48/20/22 - Harmful: danger of serious damage to health by prolonged exposure through inhalation and if swallowed
R63 - Possible risk of harm to the unborn child
R67 - Vapours may cause drowsiness and dizziness
Safety Codes:
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36/37 - Wear suitable protective clothing and gloves
Hazard Symbols:
Xi
Hazard symbol Xi
Storage temperature :
-20°C
RID/ADR certification :
UN 1888 6.1 / PG 3
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Alternative Distributors of [1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Jinan Great Chemical Co., Ltd.

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