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D,L-O-Desmethyl Venlafaxine

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Formula: C16H25NO2
CAS: 93413-62-8

Identification

Structural Formula
D,L-O-Desmethyl Venlafaxine
CAS:
93413-62-8
EINECS:
Molecular Formula:
C16H25NO2
MDL:
MFCD00871934
SMILES:
CN(C)CC(C1=CC=C(C=C1)O)C2(CCCCC2)O
Synonym:
dl-o-desmethylvenlafaxin ; dvs 233 ; o-desmethylvenlafaxine ; desvenlafaxine ; desmethylvenlafaxine ; wy-45233 ; o-desmethylvenlafaxin ; o-desmethylvenlafaxine(dl) ; desvenlafaxine impurity c ; desvenlafaxine base


Description

D,L-O-Desmethyl Venlafaxine is a metabolite of Venlafaxine. Venlafaxine is a derivative of phenylethylamine which is reported to facilitate neurotransmission within the central nervous system via blocking the presynaptic reuptake of neuroamines such as serotonin (5-hydroxytryptamine; 5-HT) and noradrenaline (norepinephrine). Velanfaxine is also reported to be a weak inhibitor of dopamine reuptake. In vitro studies indicate that Venlafaxine does not demonstrate significant activity for muscarinic, histaminergic or α-1 adrenergic receptors. The metabolism of venlafaxine is reported to occur by cytochrome P450 (CYP) enzyme CYP2D6 yielding O-desmethylvenlafaxine. A lesser metabolite, N-desmethylvenlafaxine is produced by CYP3A4.


Suppliers

Carbone Scientific Co., Ltd.
CS22686804
Santa Cruz Biotechnology, Inc.
207494
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Prices & Availability




Data is processed


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Properties for D,L-O-Desmethyl Venlafaxine

Molecular Weight:
263.38 g·mol−1
Density:
~1.1 g/cm3 (Predicted)
Melting point:
208-213 °C
Boiling point:
403.8° C at 760 mmHg
Solubility:
Soluble in DMSO (3 mg/ml), methanol (sparingly), and water (3.7 g/l at 25° C).
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Safety & Transport Information

Risk Codes:
R11 - Highly flammable
R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed
R36 - Irritating to eyes
R39/23/24/25 - Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed
Safety Codes:
S16 - Keep away from sources of ignition - No smoking
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36/37 - Wear suitable protective clothing and gloves
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
S7 - Keep container tightly closed
Hazard Symbols:
F, T, Xi
Hazard symbol T Hazard symbol F Hazard symbol Xi
Storage temperature :
-20 °C Freezer
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Alternative Distributors of [D,L-O-Desmethyl Venlafaxine]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Bepharm Ltd.

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Mol File:
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MSDS:
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