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Cytochalasin C

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Formula: C30H37 N O6
CAS: 22144-76-9
search Element: cytochalasin

Identification

Structural Formula
Cytochalasin C
CAS:
22144-76-9
EINECS:
Molecular Formula:
C30H37 N O6
MDL:
MFCD00066080
SMILES:
CC1CC=CC2C(C(=C(C3C2(C(C=CC(C1=O)(C)O)OC(=O)C)C(=O)NC3CC4=CC=CC=C4)C)C)O
Synonym:
(7s,13e,16s,18r,19e,21r)-methyl-10-phenyl ; cytochalasin c from metarrhirium anisopl iae ; 1h-cycloundec[d]isoindole,[11]cytochalasa-5,13,19-triene-1,17-dione deriv. ; cytochalasin-c from metarrhizium*anisopliae ; (11)cytochalasa-5,13,19-triene-1,17-dione,21-(acetoxy)-7,18-dihydroxy-16,18-di ; cytochalasin c from metarrhizium anisopliae ; cytochalasin c(rg) ; 1h-cycloundec[d]isoindole-1,11(2h)-dione,15-(acetyloxy)-3,3a,6,6a,9,10,12,15-octahydro-6,12-dihydroxy-4,5,10,12-tetramethyl-3-(phenylmethyl)-,[3s-(3r*,3as*,6r*,6as*,7e,10r*,12s*,13e,15s*,15as*)]- ; 7(s),18-dihydroxy-16(s),18(r)-dimethyl-10-phenyl[11]cytochalasa-5,13(e),19(e)-triene-1,17-dione 21(r)-acetate ; [11]cytochalasa-5,13,19-triene-1,17-dione,21-(acetyloxy)-7,18-dihydroxy-16,18-dimethyl-10-phenyl-,(7s,13e,16s,18r,19e,21r)- ; cytochalasin c ; 1h-cycloundec[d]isoindole-1,11(2h)-dione,3-benzyl-3,3a,6,6a,9,10,12,15-octahydro-6,12,15-trihydroxy-4,5,10,12-tetramethyl-,15-acetate (8ci)


Description

Cytochalasin C is used in actin polymerization studies. Cytochalasins are potent mycotoxins which bind to the barbed end of actin filaments resulting in inhibition of both the association and dissociation of subunits. Used as a tool for cytological research. These fungal toxins are related by their chemical structure characterized by a highly substituted hydrogenated isoindole ring to which is fused a macrocyclic ring. Cytochalasin C has shown to be 10 times less toxic in mice than cytochalasin D, but with essentially the same biological effectiveness against cells in culture.
Other Cytochalasins available: Cytochalasin A; cytochalasin B (sc-3519); Cytochalasin E, Aspergillus clavatus (sc-202561); Cytochalasin H (sc-202119); Cytochalasin J (sc-202120)


Suppliers

Iris Biotech GmbH
LS-1024
Leap Chem Co., Ltd
LC5041512
Santa Cruz Biotechnology, Inc.
202118
Dayang Chem (Hangzhou) Co.,Ltd.
DC8683472
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CAS equal suppliers

cytochalasin c from metarrhizium anisopliae
Indofine Chemical Co, Inc.
021563

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Properties for Cytochalasin C

Molecular Weight:
507.62 g·mol−1
Density:
1.24 g/cm3
Melting point:
260-264°C
Boiling point:
714.3°C at 760 mmHg
Flash point:
385.8°C
Solubility:
methylene chloride: 5 mg/mL, clear, colorless
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Safety & Transport Information

Risk Codes:
R26/27/28 - Very toxic by inhalation, in contact with skin and if swallowed
R63 - Possible risk of harm to the unborn child
Safety Codes:
S28 - After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer)
S36/37 - Wear suitable protective clothing and gloves
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
Hazard Classes:
6.1(a)
Hazard Symbols:
T+, T
Hazard symbol T Hazard symbol T+
Storage temperature :
-20°C
RID/ADR certification :
UN 1544 6.1 / PG 2
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Alternative Distributors of [Cytochalasin C]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

ABCR GmbH & Co. KG | Cfm Oskar Tropitzsch GmbH | BOC Sciences | Fermentek Ltd. | Jinan Haohua Industry Co., Ltd. | Clearsynth Canada INC.

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