Carboplatin | CAS 41575-94-4 | Chemical-Suppliers

Element: carboplatin

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C-S » Chemicals » carboplatin-PX1148006

Identification

Carboplatin

CAS:

41575-94-4

EINECS:

255-446-0

Molecular Formula:

C₆H₁₂N₂O₄Pt

MDL:

MFCD00070464

SMILES:

C1CC(C1)(C(=O)[O-])C(=O)[O-].N.N.[Pt+4]

Synonym:

cbdca ; carboplat ; nsc-241240 ; carbopaltin ; carbonplatin ; carboplatin ; jm-8 ; carboplatinum ; ercar ; paraplatin

Description

Carboplatin is a second generation potent platinum-based antineoplastic agent that is believed to form inter- and intrastrand DNA adducts which activate signaling pathways culminating in apoptosis. The development of carboplatin was inspired from the efficacy of its progenitor, Cisplatin, the first of this class of antineoplastic agents. Carboplatin displays potent antitumor activity and lower nephrotoxicity than Cisplatin. The action of this group of platinum-based compounds is primarily attributed to DNA adduct formation, however, these molecules also bind other biological molecules, including enzymes, which might play a role in their mechanism of action.

Suppliers

H&Z Industry Co.,Ltd

HIC220880

Aozeal Certified Standards (AOCS), Inc.

C0091.00

Forum Products Ltd.

FP209627

Guangzhou Topwork Chemical Co., Ltd.

GTC3961584

Alfa (A Johnson Matthey Company)

A3521056

Xiamen Equation Chemical Co.,Ltd

XECC3521760

Hainan Zhongxin Chemical Co., Ltd.

HZC3741496

Daming Changda Co., Ltd.

DC264792

CSNpharm, Inc.

CSN10551

Hangzhou Keying Chem Co., Ltd.

HKC3301320

scienTEST - bioKEMIX GmbH

S-B2751100

Hangzhou Ocean Chemical Co., Ltd.

HOC3631452

Finetech Industry Limited

FIL2751100

Hefei Hirisun Pharmatech Co., Ltd

HR130397

AK Scientific, Inc.

AS209627

Xingrui Industry Co., Limited

XIL3191276

BOC Sciences

BS132396

Leap Chem Co., Ltd

LC198594

Santa Cruz Biotechnology, Inc.

202093

Dayang Chem (Hangzhou) Co.,Ltd.

DC3411364

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Prices & Availability

Data is processed

Properties for Carboplatin

Molecular Weight:

371.25 g·mol−1

Melting point:

228-230 °C

Solubility:

Soluble in water (10 mg/ml), saline, DMSO (<1 mg/ml), and ethanol (<1 mg/ml).

Hazard Statements

GHS03
Harmful

Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, categories 2, 3
Eye irritation, category 2A
Skin sensitization, category 1
Specific target organ toxicity following single exposure, category 3
- Respiratory tract irritation
- Narcotic effects

Not used

with the "skull and crossbones" pictogram
for skin or eye irritation if:
the "corrosion" pictogram also appears
the "health hazard" pictogram is used to indicate respiratory sensitization

GHS08
Health hazard

Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A, 1B, 2
Carcinogenicity, categories 1A, 1B, 2
Reproductive toxicity, categories 1A, 1B, 2
Specific target organ toxicity following single exposure, categories 1, 2
Specific target organ toxicity following repeated exposure, categories 1, 2
Aspiration hazard, categories 1, 2

Safety & Transport Information

Risk Codes:

R20/21 - Harmful by inhalation and in contact with skin
R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed
R42/43 - May cause sensitization by inhalation and skin contact
R46 - May cause inheritable genetic damage
R61 - May cause harm to the unborn child

Safety Codes:

S22 - Do not breathe dust
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
S53 - Avoid exposure - obtain special instructions before use

Hazard Symbols:

Storage temperature :

Store at RT

RID/ADR certification :

2811

Alternative Distributors of [Carboplatin]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Downloads

Mol File:

-/-

MSDS:

-/-

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